Lidan You

PhD, P.Eng., FCSME

Professor, Mechanical Engineering
Erwin Edward Hart Professor in Mechanical and Industrial Engineering

Tel: 416-978-5736
Office: MC316
Research Group: Cellular Biomechanics Laboratory (CBL)

Research Areas

Mechanics & Design

Research Interests

Muscular skeletal biomechanics; bone cell mechanobiology; bone tissue engineering; bone modelling and remodelling; advanced microfluidics system for bone cell mechanotransduction study; osteoporosis prevention and treatment; and bone regeneration.


Lidan You is a Professor at the University of Toronto with cross-appointments in the Department of Mechanical & Industrial Engineering (MIE) and the Institute of Biomaterials and Biomedical Engineering (IBBME). She received her PhD degree in mechanical engineering from the City University of New York in 2002. Dr. You continued her postdoc training at Stanford University before she joined the University of Toronto as a faculty member in 2006.

Dr. You received the Early Researcher Award from the Ontario Ministry of Research and Innovation in 2009 and the Duggan Medal from Canadian Society of Mechanical Engineering (CSME) in 2011. She is a registered Professional Engineer in Ontario, and a member of the Orthopedics Research Society, the American Society of Mechanical Engineers, the Canadian Society of Mechanical Engineers, the Biomedical Engineering Society, and the American Society of Bone and Mineral Research.

Dr. You is the director of Cellular Biomechanics Laboratory at U of T. Her research is focused on solving biomechanical questions in muscular skeletal system at the cellular level. In specific, her team is working on the anti-resorptive effect of mechanical loading on bone tissue; pressure effect on bone cell mechanotransduction; osteogenic potential of high frequency low magnitude vibration on bone adaptation; angiogenesis involvement in initiation of bone resorption under disuse condition; the advanced microfluidic system for bone cell mechanotransduction study; the role of focal adhesion assembly in cell mechanosensitivity using micropatterned surface; and the development of advanced artificial bone matrix by employing novel microfabrication technologies.

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